Donor-Recipient Matching Is Important but Age Matching Alone Is Insufficient
نویسندگان
چکیده
منابع مشابه
Personalized Donor-Recipient Matching for Organ Transplantation
Organ transplants can improve the life expectancy and quality of life for the recipient but carries the risk of serious post-operative complications, such as septic shock and organ rejection. The probability of a successful transplant depends in a very subtle fashion on compatibility between the donor and the recipient – but current medical practice is short of domain knowledge regarding the co...
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1 Institute of Immunology and Experimental Therapy, Polish Academy of Science, Wroclaw, Poland 2National Bone Marrow Donor Registry, Lower Silesian Center for Cellular Transplantation, Wroclaw, Poland 3 International Research Group on Hematopoietic Cell Transplantation (IRGHET), Foundation Jean Dausset, Paris, France 4Anthony Nolan Research Institute, Royal Free Hospital, London, UK 5Section of...
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The relative importance of various human leukocyte antigen (HLA) loci and the resolution level at which they are matched has not been fully defined for unrelated donor transplantation. To address this question, National Marrow Donor Program data from 3857 transplantations performed from 1988 to 2003 in the United States were analyzed. Patient-donor pairs were fully typed for HLA-A, -B, -C, -DRB...
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Experimentally naive mice matched the proportions of their temporal investments (visit durations) in two feeding hoppers to the proportions of the food income (pellets per unit session time) derived from them in three experiments that varied the coupling between the behavioral investment and food income, from no coupling to strict coupling. Matching was observed from the outset; it did not impr...
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Primitive mammalian neural stem cells (NSCs), arising during the earliest stages of embryogenesis, possess pluripotency in embryo chimera assays in contrast to definitive NSCs found in the adult. We hypothesized that adhesive differences determine the association of stem cells with embryonic cells in chimera assays and hence their ability to contribute to later tissues. We show that primitive N...
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ژورنال
عنوان ژورنال: Transplantation
سال: 2019
ISSN: 0041-1337
DOI: 10.1097/tp.0000000000002593